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T cell warriors need their R & R

T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors. However, without rest and maintenance T cells can die and leave their hosts more susceptible to pathogens, scientists report.

Learning from nature: Biosynthesis of cyanobacterin opens up new class of natural compounds for applications in medicine and agriculture

Researchers have succeeded in understanding the biosynthetic mechanisms for the production of the natural product cyanobacterin, which is produced in small quantities by the cyanobacteria Scytonema hofmanni. In the process, they also discovered a new class of enzymes for building carbon-carbon bonds. The (bio)chemists are thus significantly expanding the biocatalytic...

An arms race that plays out in a single genome

We often think of biological arms races occurring between the immune system and pathogens, or predator and prey, but biologists have now discovered an example that plays out within a single genome. Their work in fruit flies may have implications for key biological processes in humans, including fertility and even...