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A better way to make RNA drugs

RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the...

Researchers develop a way to make lifesaving phages accessible, transportable and much easier to use

Researchers have developed a simple way to bring bacteriophage therapy into much closer reach for clinicians struggling to save patients with antimicrobial-resistant infections. The technology makes it possible to sort through hundreds or even thousands of phages in less than two hours to identify which will respond to a particular...

Opening the right doors: ‘Jumping gene’ control mechanisms revealed

International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical...