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Study provides an explanation and potential solution for severe graft-versus-host disease

Researchers found that alterations in the gut microbiome that are linked to graft-versus-host disease severity are connected to an increase in oxygen levels in the intestine that follows immune-mediated intestinal damage. Pharmacologically reducing intestinal oxygen levels alleviated the microbial imbalance and reduced the severity of the condition in animal models.

Mapping Mexico’s dengue fever hotspots

Scientists have analyzed data from Mexico's Ministry of Health to identify dengue fever hotspots. Working with epidemiologists at the University of North Texas and Universidad Autónoma de Nuevo León, the team calculated environmental and socioeconomic risk factors and mapped areas where severe outbreaks occur.

Discovery of a circovirus involved in human hepatitis

Scientists have identified a previously unknown species of circovirus, provisionally named human circovirus 1 (HCirV-1). Circoviruses are a family of small, highly resistant DNA viruses that were initially identified in 1974 in various animal species, where they can cause respiratory, renal, dermatological and reproductive problems. HCirV-1 is a novel virus...