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Treatments for poxviruses — including those causing mpox and smallpox — may already exist in licensed drugs

The drug tecovirimat is currently in use for the treatment of mpox -- the disease caused by monkeypox virus -- that spread worldwide in 2022. Tecovirimat is an anti-poxviral drug, and its use is driving the emergence of drug-resistant variants of the monkeypox virus. Scientists have identified how monkeypox virus...

Remission from HIV-1 infection: Discovery of broadly neutralizing antibodies that contribute to virus control

Some HIV-1 carriers who have received an early antiretroviral treatment during several years are able to control the virus for a long term after treatment interruption. However, the mechanisms enabling this post-treatment control have not been fully elucidated. Scientists have now investigated and revealed how neutralizing antibodies, including those described...